BDBM507123 US11046675, Example 1002

SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)cc3CCN(CC(O)=O)Cc23)cccc1-c1ccc2OCCOc2c1

InChI Key InChIKey=QIOYVMNPFVSENV-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 507123   

TargetProgrammed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent

LigandBDBM507123(US11046675, Example 1002)Copy SMILESCopy InChI

Affinity DataIC50:  775nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI